Title | Simultaneous elimination of carryover contamination and detection of DNA with uracil-DNA-glycosylase-supplemented loop-mediated isothermal amplification (UDG-LAMP). |
Publication Type | Journal Article |
Year of Publication | 2014 |
Authors | Hsieh K, Mage PL, Csordas AT, Eisenstein M, H Soh T |
Journal | Chem Commun (Camb) |
Volume | 50 |
Issue | 28 |
Pagination | 3747-9 |
Date Published | 2014 Apr 11 |
ISSN | 1364-548X |
Abstract | We report a one-pot, closed-vessel enzymatic assay that eliminates carryover contamination while preserving robust DNA amplification in loop-mediated isothermal amplification (LAMP), providing reliable and rapid detection of target DNA in contaminated samples. |
DOI | 10.1039/c4cc00540f |
Alternate Journal | Chem. Commun. (Camb.) |
PubMed ID | 24577617 |