Aptamer-based cell imaging reagents capable of fluorescence switching.

TitleAptamer-based cell imaging reagents capable of fluorescence switching.
Publication TypeJournal Article
Year of Publication2014
AuthorsJung YKyung, Woo M-A, H Soh T, Park HGyu
JournalChem Commun (Camb)
Volume50
Issue82
Pagination12329-32
Date Published2014 Sep 18
ISSN1364-548X
Abstract

We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.

DOI10.1039/c4cc03888f
Alternate JournalChem. Commun. (Camb.)
PubMed ID25182171